98N12-5
Based on 1 publication(s) in Google Scholar
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.0%
- CAS No.: 917572-74-8
- 화학식: C81H163N9O5
- 분자량:1343.22
-
보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
-
Biological Activity
-
Chemical Information
-
용액&용해도
- 순도&문서
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 98N12-5
More
Biological Activity
Chemical Information
-
CAS No. 917572-74-8
-
Appearance Solid
-
분자량 1343.22
-
화학식 C81H163N9O5
-
Color Off-white to light yellow
-
SMILES
CCCCCCCCCCCCNC(CCN(CCN(CCC(NCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCC)=O)CCNCCN(CCC(NCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCC)=O)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Adv Sci (Weinh)
2026 Mar 24:e17931. PMID: 41875360
용액&용해도
THF : 50 mg/mL (37.22 mM; Need ultrasonic)
DMSO : 50 mg/mL (37.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
-
Data Sheet (267 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Akinc A, Goldberg M, Qin J, et al. Development of lipidoid-siRNA formulations for systemic delivery to the liver. Mol Ther. 2009;17(5):872-879. [Content Brief]
[2]. Nguyen DN, Chen SC, Lu J, et al. Drug delivery-mediated control of RNA immunostimulation. Mol Ther. 2009;17(9):1555-1562. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| THF / DMSO | 1 mM | 0.7445 mL | 3.7224 mL | 7.4448 mL | 18.6120 mL |
| 5 mM | 0.1489 mL | 0.7445 mL | 1.4890 mL | 3.7224 mL | |
| 10 mM | 0.0744 mL | 0.3722 mL | 0.7445 mL | 1.8612 mL | |
| 15 mM | 0.0496 mL | 0.2482 mL | 0.4963 mL | 1.2408 mL | |
| 20 mM | 0.0372 mL | 0.1861 mL | 0.3722 mL | 0.9306 mL | |
| 25 mM | 0.0298 mL | 0.1489 mL | 0.2978 mL | 0.7445 mL | |
| 30 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.6204 mL |
Powered by Bioz