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Cat. No.: HY-B0107A

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Acitretin sodium

(Synonyms: Ro 10-1670 sodium)

4 Cited Publications

고객리뷰

Based on 4 publication(s) in Google Scholar

Acitretin (Ro 10-1670) sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin sodium also can be used for the research of Alzheimer’s disease.

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CAS No.: 925701-88-8
화학식: C₂₁H₂₅NaO₃
분자량:348.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Acitretin sodium Chemical Structure

CAS No.: 925701-88-8

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Biological Activity

제품 설명

Acitretin (Ro 10-1670) sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin sodium also can be used for the research of Alzheimer’s disease^[1]^[2]^[3].

All RAR/RXR Isoforms :

In Vivo

Acitretin (10 mg/kg; i.p. for 7 days) increases IL-6 in the central nervous system of Alzheimer’s disease model mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 925701-88-8
분자량 348.41
화학식 C₂₁H₂₅NaO₃
SMILES

CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=C\C=C\C(C)=C\C(O[Na])=O
Synonyms

Ro 10-1670 sodium
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

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Eur J Pharmacol

Adapalene suppressed the proliferation of melanoma cells by S-phase arrest and subsequent apoptosis via induction of DNA damage. [Abstract]

2019 May 15:851:174-185. PMID: 30836068
J Biol Chem

A cell-based assay for retinaldehyde dehydrogenase activity: Retinoid quantification as an alternative to current fluorescence-based approaches. [Abstract]

2026 Jan 29;302(3):111211. PMID: 41617028
Chin J Integr Med

Total Glucosides of Paeony Regulate Immune Imbalance Mediated by Dermal Mesenchymal Stem Cells in Psoriasis Mice. [Abstract]

2023 Jun;29(6):517-525. PMID: 37222920
Fundam Clin Pharmacol

The third-generation retinoid adapalene triggered DNA damage to induce S-phase arrest in HaCat cells. [Abstract]

2020 Jun;34(3):380-388. PMID: 31808972

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee CS, et al. A review of acitretin, a systemic retinoid for the treatment of psoriasis. Expert Opin Pharmacother. 2005 Aug;6(10):1725-34. [Content Brief]

[2]. Seng?r B, et al. Effects of acitretin on spermatogenesis of rats. J Eur Acad Dermatol Venereol. 2006 Jul;20(6):689-92. [Content Brief]

[3]. Guilherme MDS, et, al. The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients. Front Aging Neurosci. 2019 Jul 23;11:182. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Acitretin sodium

4 Cited Publications

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- In Vivo
Chemical Information
Publications (4)
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References

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Acitretin sodium

Publications Citing Use of MedChemExpress (MCE) Acitretin sodium

All RAR/RXR Isoforms

Biological Activity

Chemical Information

Publications (4)

순도&문서

References

Calculators

Help & FAQs

Acitretin sodium Related Classifications

HY-B0107A Related Classifications