CP-060
CP-060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities.
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- CAS No.: 180090-15-7
- 화학식: C30H42N2O5S
- 분자량:542.73
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
All Calcium Channel Isoforms
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Biological Activity
제품 설명
In Vitro
CP-060 (0.5, 5 μM) inhibits rabbit LDL oxidation induced by soybean lipoxygenase by 12.9% and 3.0%, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 180090-15-7
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분자량 542.73
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화학식 C30H42N2O5S
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SMILES
O=C1N(CCCN(CCOC2=CC=C(OCO3)C3=C2)C)C(C4=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C4)SC1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Ca2+ Staining Technique
Ca2+ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca2+ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.
순도&문서
References
[1]. Kato T, et al. Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 1. 2-(3, 5-di-tert-butyl-4-hydroxyphenyl)-3-(aminopropyl)thiazolidinones. J Med Chem. 1998 Oct 22;41(22):4309-16. [Content Brief]
[2]. Kato T, et al. Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 2. Structure-activity relationships of thiazolidinone derivatives. J Med Chem. 1999 Aug 12;42(16):3134-46. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP-060 Related Classifications
HY-U00354 Related Classifications
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