Cat. No.: HY-B0528A

Octopamine hydrochloride

(Synonyms: (±)-p-Octopamine hydrochloride)

5 Cited Publications

고객리뷰

Based on 5 publication(s) in Google Scholar

Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 99.90%
CAS No.: 770-05-8
화학식: C₈H₁₂ClNO₂
분자량:189.64

보관:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Octopamine hydrochloride Chemical Structure

CAS No.: 770-05-8

사이즈

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재고

수량

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Publications (5)
용액&용해도
- In Vitro
- In Vivo
순도&문서
References
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]^[2]

Human Endogenous Metabolite

α2-adrenergic receptor

All Adrenergic Receptor Isoforms :

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	978 nM Compound: OA	Agonist activity at Chilo suppressalis (rice stem borer) tyramine receptor TyR1 expressed in HEK293 cells assessed as reduction in forskolin-induced cAMP accumulation incubated for 20 min Agonist activity at Chilo suppressalis (rice stem borer) tyramine receptor TyR1 expressed in HEK293 cells assessed as reduction in forskolin-induced cAMP accumulation incubated for 20 min	[PMID: 23129510]

In Vitro

Octopamine has a prominent role in influencing multiple physiological events: (a) as a neuromodulator, it regulates desensitization of sensory inputs, arousal, initiation, and maintenance of various rhythmic behaviors and complex behaviors such as learning and memory; (b) as a neurotransmitter, it regulates endocrine gland activity; and (c) as a neurohormone, it induces mobilization of lipids and carbohydrates. Octopamine exerts its effects by binding to specific proteins that belong to the superfamily of G protein-coupled receptors and share the structural motif of seven transmembrane domains^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 770-05-8
Appearance Solid
분자량 189.64
화학식 C₈H₁₂ClNO₂
Color White to off-white
SMILES

OC(C1=CC=C(O)C=C1)CN.Cl
Synonyms

(±)-p-Octopamine hydrochloride
Structure Classification
- Phenols
- Monophenols
Initial Source
- Endogenous metabolite
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (5)

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Journal Impact Factor

Cell Res

Light sensing enhances thermotolerance and competitive fitness via serotonergic signaling in an eyeless organism. [Abstract]

2026 Apr;36(4):286-299. PMID: 41764323
Nat Commun

Gut microbiota modulates aversive learning and memory of honeybees (Apis mellifera). [Abstract]

2025 Dec 18;16(1):11196. PMID: 41413037
Insect Mol Biol

Octopamine terminates sex pheromone biosynthesis by suppressing PBAN signal in moths. [Abstract]

2022 Oct;31(5):647-658. PMID: 35652818
bioRxiv

2025 Aug 29.
bioRxiv

2025 April 21.

용액&용해도

In Vitro:

DMSO : ≥ 100 mg/mL (527.31 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : ≥ 50 mg/mL (263.66 mM)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

5.2731 mL

26.3657 mL

52.7315 mL

5 mM

1.0546 mL

5.2731 mL

10.5463 mL

10 mM

0.5273 mL

2.6366 mL

5.2731 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

In Vivo:

Working Solution

For the following dissolution methods, please prepare the working solution directly:

It is recommended to prepare fresh solutions and use them promptly within a short period of time.

The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS

Solubility: 100 mg/mL (527.31 mM); Clear solution; Need ultrasonic

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Roeder T. Octopamine in invertebrates. Prog Neurobiol. 1999;59(5):533-561. [Content Brief]

[2]. Farooqui T. Octopamine-mediated neuromodulation of insect senses. Neurochem Res. 2007;32(9):1511-1529. [Content Brief]

[3]. Axelrod J, et al. Octopamine. Nature. 1977;265(5594):501-504. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O / DMSO	1 mM	5.2731 mL	26.3657 mL	52.7315 mL	131.8287 mL
	5 mM	1.0546 mL	5.2731 mL	10.5463 mL	26.3657 mL
	10 mM	0.5273 mL	2.6366 mL	5.2731 mL	13.1829 mL
	15 mM	0.3515 mL	1.7577 mL	3.5154 mL	8.7886 mL
	20 mM	0.2637 mL	1.3183 mL	2.6366 mL	6.5914 mL
	25 mM	0.2109 mL	1.0546 mL	2.1093 mL	5.2731 mL
	30 mM	0.1758 mL	0.8789 mL	1.7577 mL	4.3943 mL
	40 mM	0.1318 mL	0.6591 mL	1.3183 mL	3.2957 mL
	50 mM	0.1055 mL	0.5273 mL	1.0546 mL	2.6366 mL
	60 mM	0.0879 mL	0.4394 mL	0.8789 mL	2.1971 mL
	80 mM	0.0659 mL	0.3296 mL	0.6591 mL	1.6479 mL
	100 mM	0.0527 mL	0.2637 mL	0.5273 mL	1.3183 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

Octopamine hydrochloride

5 Cited Publications

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Octopamine hydrochloride

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Publications Citing Use of MedChemExpress (MCE) Octopamine hydrochloride

All Adrenergic Receptor Isoforms

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Publications (5)

용액&용해도

순도&문서

References

Help & FAQs

Complete Stock Solution Preparation Table

Octopamine hydrochloride Related Classifications

HY-B0528A Related Classifications