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Cat. No.: HY-19373

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RWJ-445167

(Synonyms: 3DP-10017)

RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with K_i of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

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CAS No.: 226566-43-4
화학식: C₁₈H₂₄N₆O₅S
분자량:436.49

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

RWJ-445167 Chemical Structure

CAS No.: 226566-43-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with K_i of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

IC₅₀ & Target

Ki: 4.0 nM (thrombin), 230 nM (factor Xa)^[1]

Chemical Information

CAS No. 226566-43-4
분자량 436.49
화학식 C₁₈H₂₄N₆O₅S
SMILES

O=C(NCCONC(N)=N)CN1C(C)=CC=C(NS(=O)(C2=CC=CC(C)=C2)=O)C1=O
Synonyms

3DP-10017
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. RWJ-445167, et al. Exploration of potential prodrugs of RWJ-445167, an oxyguanidine-based dual inhibitor of thrombin and factor Xa. Chem Biol Drug Des. 2006 Jul;68(1):29-36. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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RWJ-445167

Apixaban

Edoxaban

Apixaban (Standard)

Otamixaban

Edoxaban tosylate monohydrate

Edoxaban (Standard)

Rivaroxaban

Fondaparinux sodium

Rivaroxaban (Standard)

5-R-Rivaroxaban

Betrixaban

Edoxaban tosylate

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

RWJ-445167

Apixaban

Edoxaban

Apixaban (Standard)

Otamixaban

Edoxaban tosylate monohydrate

Edoxaban (Standard)

Rivaroxaban

Fondaparinux sodium

Rivaroxaban (Standard)

5-R-Rivaroxaban

Betrixaban

Edoxaban tosylate

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RWJ-445167 Related Classifications

HY-19373 Related Classifications

Bioz