Copy Link Print Information

Fosribnicotinamide

(Synonyms: β-Nicotinamide mononucleotide; β-NM; NMN)
35 Cited Publications
고객리뷰

Based on 35 publication(s) in Google Scholar

Fosribnicotinamide (β-nicotinamide mononucleotide) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity : 99.94%
  • CAS No.: 1094-61-7
  • 화학식: C11H15N2O8P
  • 분자량:334.22
  • 보관:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Fosribnicotinamide Chemical Structure
    Fosribnicotinamide Chemical Structure
  • Experimental Validation Results for Fosribnicotinamide
  • Experimental Validation Results for Fosribnicotinamide
  • Experimental Validation Results for Fosribnicotinamide
  • Experimental Validation Results for Fosribnicotinamide
  • Experimental Validation Results for Fosribnicotinamide
  • Experimental Validation Results for Fosribnicotinamide
CAS No.: 1094-61-7
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Fosribnicotinamide:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • Protocol
  • 순도&문서
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Fosribnicotinamide

More
Customer Validation & Images
Bio/Physico-chemical AssayWBIn Vivo Efficacy StudyFlow Cytometry
  • Bio/Physico-chemical Assay
  • In Vivo Efficacy Study
  • Flow Cytometry
  • Flow Cytometry
  • In Vivo Efficacy Study
  • WB

All Endogenous Metabolite Isoforms

More

Keywords

MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Fosribnicotinamide Chemical Structure
    Fosribnicotinamide Chemical Structure
    1/16
  • 1/16

    Fosribnicotinamide purchased from MedChemExpress. Usage Cited in: Theranostics. 2024 Apr 28;14(7):2794-2815. [Abstract]

    Customer Validation
     RAW264.7 cells were treated with FK866 (1 nM) and β-NMN (100 μΜ) 30 min before the addition of TGF-β1 (20 ng/mL) for 24 h，ELISA assay of NAMPT releasing in the culture supernatant (left), Quantification of the intracellular NAD level using a commercial kit (right).

  • 1/16

    Fosribnicotinamide purchased from MedChemExpress. Usage Cited in: Cell Metab. 2021 Jan 5;33(1):110-127.e5. [Abstract]

    Customer Validation
     Tumor growth curves and tumor burdens in C57BL/6 mice injected subcutaneously with sgCtrl or sgNampt liver cancer cells (Hepa1–6) for 3 weeks (n = 6) and C57BL/6 mice injected subcutaneously with Hepa1–6 cells with solvent control (Ctrl) or NMN (Fosribnicotinamide;300 mg/kg body weight; daily;intraperitoneal injection for 2 weeks beginning on day 7 after LLC cells, Pan02 cells, or Hepa1-6-CD38 cells were subcutaneously implanted).

  • 1/16

    Fosribnicotinamide purchased from MedChemExpress. Usage Cited in: Cell Metab. 2021 Jan 5;33(1):110-127.e5. [Abstract]

    Customer Validation
     Representative flow staining indicated cells in tumor xenograft of indicated groups.(NMN, Fosribnicotinamide;300 mg/kg body weight; daily;intraperitoneal injection for 2 weeks beginning on day 7 after LLC cells, Pan02 cells, or Hepa1-6-CD38 cells were subcutaneously implanted)

  • 1/16

    Fosribnicotinamide purchased from MedChemExpress. Usage Cited in: Cell Metab. 2021 Jan 5;33(1):110-127.e5. [Abstract]

    Customer Validation
     Representative flow staining (left panel) and frequency (right panel) of CD8+ T cells and PD-1+ CD8+ T cells in tumor xenograft of indicated groups ((NMN, Fosribnicotinamide;300 mg/kg body weight; daily,ip; PD-L1 antibodies (100 μg of anti-PD-L1 per mouse; twice a week) or combination via intraperitoneal injection for 2 weeks beginning on day 7 after LLC cells, Pan02 cells, or Hepa1-6-CD38 cells were subcutaneously implanted).

  • 1/16

    Fosribnicotinamide purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19626-19634. [Abstract]

    Customer Validation
     p53−/− mice were treated per divided lowdose Dox protocol and with either vehicle control or NMN (Fosribnicotinamide; 500 mg/kg, i.p., 3 times per week on alternating days) over the duration of the entire study. Unless indicated, all analyses were performed at study week 10. LV ejection fraction (LVEF) of p53−/−mice treated with Dox only or Dox plus NMN was measured by echocardiogram at study week 7 and 10 (n = 8). Mitochondrial respiration and ATP levels were measured in cardiac tissue (n ≥ 3).

  • 1/16

    Fosribnicotinamide purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19626-19634. [Abstract]

    Customer Validation
     p53−/− mice were treated per divided lowdose Dox protocol and with either vehicle control or NMN (Fosribnicotinamide; 500 mg/kg, i.p., 3 times per week on alternating days) over the duration of the entire study. Unless indicated, all analyses were performed at study week 10. Immunoblot of representative mtDNA-encoded protein MT-CO1 in cardiac tissue. GAPDH is shown as protein loading control.

  • Fosribnicotinamide