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Cat. No.: HY-121782

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A 65281

A 65281 is a potent DNA gyrase inhibitor with an IC₅₀ value of 0.1 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. A 65281 inhibits P4 DNA unknotting with an IC₅₀ value of 8 µg/mL.

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CAS No.: 111279-49-3
화학식: C₁₇H₁₆F₂N₄O₂S
분자량:378.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

A 65281 Chemical Structure

CAS No.: 111279-49-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 111279-49-3
분자량 378.40
화학식 C₁₇H₁₆F₂N₄O₂S
SMILES

O=C1NSC(N(C2=C3C=C(C(N4CCNCC4)=C2F)F)C5CC5)=C1C3=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kohlbrenner WE, et al. Induction of calf thymus topoisomerase II-mediated DNA breakage by the antibacterial isothiazoloquinolones A-65281 and A-65282. Antimicrob Agents Chemother. 1992 Jan;36(1):81-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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A 65281

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

A 65281 Related Classifications

HY-121782 Related Classifications