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Cat. No.: HY-129407

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AAF-CMK TFA

(Synonyms: Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II)

AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

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CAS No.: 184901-82-4
화학식: C₁₈H₂₃ClF₃N₃O₅
분자량:453.84

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

AAF-CMK TFA Chemical Structure

CAS No.: 184901-82-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

CAS No. 184901-82-4
분자량 453.84
화학식 C₁₈H₂₃ClF₃N₃O₅
SMILES

C[C@@H](C(N)=O)N(C([C@H](C)N)=O)[C@@H](CC1=CC=CC=C1)C(CCl)=O.O=C(O)C(F)(F)F
Synonyms

Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Macpherson, et al. Supramolecular structure of tripeptidyl peptidase II from human erythrocytes as studied by electron microscopy, and its correlation to enzyme activity. Biochem. J. 248(1), 259-263 (1987).

Calculators

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Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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AAF-CMK TFA

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AAF-CMK TFA Related Classifications

HY-129407 Related Classifications