Antibacterial agent 229
Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM.
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- CAS No.: 3049500-54-8
- 화학식: C16H14ClFN6OS2
- 분자량:424.90
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
제품 설명
IC50 & Target
[1]|
TOPO IV 10.88 μM (IC50) |
In Vitro
Antibacterial agent 229 (compound 8a) shows antibacterial and antifungal abilities with MIC Values of 0.0377, 0.0047, 0.0189, 0.0189, 0.0189, 0.0189, 0.0047 mM for S. aureus ATCC 25923, S. aureus ATCC 29213, E. coli ATCC 25922, P. aeruginosa ATCC 27853, C. albicans ATCC 9002, C. albicans, C. parapsilosis ATCC 22019, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3049500-54-8
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분자량 424.90
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화학식 C16H14ClFN6OS2
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SMILES
O=C1C(C2=CSC(N)=N2)=CN(C/C(C)=N/NC(N)=S)C3=CC(Cl)=C(F)C=C31
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)