Asebogenin
Asebogenin has antimalarial activity in vitro. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 520-42-3
- 화학식: C16H16O5
- 분자량:288.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KB | ED50 |
>10 μg/mL
Compound: 2, Asebogenin
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Cytotoxicity against human KB cells after 72 hrs
Cytotoxicity against human KB cells after 72 hrs
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[PMID: 8158163] |
Chemical Information
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CAS No. 520-42-3
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분자량 288.30
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화학식 C16H16O5
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SMILES
O=C(C1=C(O)C=C(OC)C=C1O)CCC2=CC=C(O)C=C2
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. [Content Brief]
[2]. Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Asebogenin Related Classifications
HY-N7314 Related Classifications
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