B I09 (Standard)
B I09 (Standard) is the analytical standard of B I09 (HY-107400). This product is intended for research and analytical applications. B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1607803-67-7
- 화학식: C16H17NO5
- 분자량:303.31
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 1230 nM (IRE-1 RNase)[1].
Chemical Information
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CAS No. 1607803-67-7
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분자량 303.31
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화학식 C16H17NO5
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SMILES
OC1=CC=C(C2=C(CNCC2)C3=O)C(O3)=C1C4OCCCO4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Ranatunga S, et al. Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J Med Chem. 2014 May 22;57(10):4289-301. [Content Brief]
[2]. Tang CH, et al. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J Clin Invest. 2014 Jun;124(6):2585-98. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)