BAY-5000
Based on 1 Customer Validation
BAY-5000 (example 32) is a pyrimidinedione derivative. BAY-5000 can be used in the synthesis of cancer-related reagents.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.26%
- CAS No.: 2639435-48-4
- 화학식: C22H14ClF3N2O3
- 분자량:446.81
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
1 μM
Compound: 36
|
Upregulation of BCAA expression in human MDA-MB-231 cells
Upregulation of BCAA expression in human MDA-MB-231 cells
|
[PMID: 36261130] |
| MDA-MB-231 | IC50 |
874 nM
Compound: 36a; BAY-069
|
Upregulation of BCAA expression in human MDA-MB-231 cells
Upregulation of BCAA expression in human MDA-MB-231 cells
|
[PMID: 36261130] |
Chemical Information
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CAS No. 2639435-48-4
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Appearance Solid
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분자량 446.81
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화학식 C22H14ClF3N2O3
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Color Off-white to light yellow
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SMILES
CC(C=CC=C1)=C1OC2=C(Cl)C3=C(C=CC=C3)C(N4C(NC(C(F)(F)F)=CC4=O)=O)=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 250 mg/mL (559.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2381 mL | 11.1904 mL | 22.3809 mL | 55.9522 mL |
| 5 mM | 0.4476 mL | 2.2381 mL | 4.4762 mL | 11.1904 mL | |
| 10 mM | 0.2238 mL | 1.1190 mL | 2.2381 mL | 5.5952 mL | |
| 15 mM | 0.1492 mL | 0.7460 mL | 1.4921 mL | 3.7301 mL | |
| 20 mM | 0.1119 mL | 0.5595 mL | 1.1190 mL | 2.7976 mL | |
| 25 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2381 mL | |
| 30 mM | 0.0746 mL | 0.3730 mL | 0.7460 mL | 1.8651 mL | |
| 40 mM | 0.0560 mL | 0.2798 mL | 0.5595 mL | 1.3988 mL | |
| 50 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1190 mL | |
| 60 mM | 0.0373 mL | 0.1865 mL | 0.3730 mL | 0.9325 mL | |
| 80 mM | 0.0280 mL | 0.1399 mL | 0.2798 mL | 0.6994 mL | |
| 100 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5595 mL |