BPH252

ADC Targets in Oncology

2026-04-10

Cell Line	Type	Value	Description	References
Erythrocyte	IC₅₀	0.83 μM Compound: NBP8	Antiparasitic activity against Plasmodium falciparum 3D7 infected in human erythrocyte assessed as intraerythrocytic growth inhibition incubated for 24 hrs followed by [3H]hypoxanthine addition by microbeta scintillation counter analysis Antiparasitic activity against Plasmodium falciparum 3D7 infected in human erythrocyte assessed as intraerythrocytic growth inhibition incubated for 24 hrs followed by [3H]hypoxanthine addition by microbeta scintillation counter analysis	[PMID: 33522236]
HFF	IC₅₀	0.55 μM Compound: 2	In vitro inhibitory concentration against the growth of Toxoplasma gondii in human foreskin fibroblast monolayer cells (HFF cells) In vitro inhibitory concentration against the growth of Toxoplasma gondii in human foreskin fibroblast monolayer cells (HFF cells)	[PMID: 15857119]
HFF	IC₅₀	0.57 μM Compound: 2	Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.15 uM, experiment 2) Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.15 uM, experiment 2)	[PMID: 15857119]
HFF	IC₅₀	1.7 μM Compound: 2	Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.55 uM, experiment 3) Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.55 uM, experiment 3)	[PMID: 15857119]
HFF	IC₅₀	1.9 μM Compound: 2	Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.62 uM, experiment 1) Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.62 uM, experiment 1)	[PMID: 15857119]
KB	ED₅₀	892 μM Compound: 72	Dose to inhibit the growth of human KB carcinoma cell line Dose to inhibit the growth of human KB carcinoma cell line	[PMID: 16162013]

Cell Line

Type

Value

Description

References

Erythrocyte

IC₅₀

0.83 μM

Compound: NBP8

Antiparasitic activity against Plasmodium falciparum 3D7 infected in human erythrocyte assessed as intraerythrocytic growth inhibition incubated for 24 hrs followed by [3H]hypoxanthine addition by microbeta scintillation counter analysis

[PMID: 33522236]

HFF

IC₅₀

0.55 μM

Compound: 2

In vitro inhibitory concentration against the growth of Toxoplasma gondii in human foreskin fibroblast monolayer cells (HFF cells)

[PMID: 15857119]

HFF

IC₅₀

0.57 μM

Compound: 2

Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.15 uM, experiment 2)

[PMID: 15857119]

HFF

IC₅₀

1.7 μM

Compound: 2

Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.55 uM, experiment 3)

[PMID: 15857119]

HFF

IC₅₀

1.9 μM

Compound: 2

Inhibitory concentration against the growth of Toxoplasma gondii overexpressing FPPS enzyme in human foreskin fibroblast monolayer cells; (control = 0.62 uM, experiment 1)

[PMID: 15857119]

ED₅₀

892 μM

Compound: 72

Dose to inhibit the growth of human KB carcinoma cell line

[PMID: 16162013]

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BPH252

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BPH252 Related Classifications

HY-126472 Related Classifications