CBIQ
Based on 1 Customer Validation
CBIQ (4-Chlorobenzo[f]isoquinoline) is a benzoisoquinoline compound. CBIQ can activate the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- ion channels and the intermediate-conductance calcium-sensitive K+ channel (KCNN4) with Kd values of 0.1 and 3.9 μM. CBIQ can be used for the research related to cystic fibrosis.
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- Purity: 99.94%
- CAS No.: 32081-28-0
- 화학식: C13H8ClN
- 분자량:213.66
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 32081-28-0
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Appearance Solid
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분자량 213.66
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화학식 C13H8ClN
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SMILES
ClC1=NC=CC2=C1C=CC=3C=CC=CC32
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Synonyms
4-Chlorobenzo[f]isoquinoline
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 31.25 mg/mL (146.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (271 KB)
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SDS (582 KB)
- English - EN (582 KB)
- Français - FR (582 KB)
- Deutsch - DE (582 KB)
- Norwegian - NO (582 KB)
- Español - ES (582 KB)
- Swedish - SV (582 KB)
- Italian - IT (582 KB)
- Portuguese - PT (582 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6803 mL | 23.4017 mL | 46.8033 mL | 117.0083 mL |
| 5 mM | 0.9361 mL | 4.6803 mL | 9.3607 mL | 23.4017 mL | |
| 10 mM | 0.4680 mL | 2.3402 mL | 4.6803 mL | 11.7008 mL | |
| 15 mM | 0.3120 mL | 1.5601 mL | 3.1202 mL | 7.8006 mL | |
| 20 mM | 0.2340 mL | 1.1701 mL | 2.3402 mL | 5.8504 mL | |
| 25 mM | 0.1872 mL | 0.9361 mL | 1.8721 mL | 4.6803 mL | |
| 30 mM | 0.1560 mL | 0.7801 mL | 1.5601 mL | 3.9003 mL | |
| 40 mM | 0.1170 mL | 0.5850 mL | 1.1701 mL | 2.9252 mL | |
| 50 mM | 0.0936 mL | 0.4680 mL | 0.9361 mL | 2.3402 mL | |
| 60 mM | 0.0780 mL | 0.3900 mL | 0.7801 mL | 1.9501 mL | |
| 80 mM | 0.0585 mL | 0.2925 mL | 0.5850 mL | 1.4626 mL | |
| 100 mM | 0.0468 mL | 0.2340 mL | 0.4680 mL | 1.1701 mL |
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