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Cat. No.: HY-171247

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CDD-1281

CDD-1281 is a highly potent and selective BMPR2 kinase inhibitor with an IC₅₀ of 1.2 nM. CDD-1281 can effectively inhibit BMP-mediated gene expression.

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CAS No.: 3034215-91-0
화학식: C₃₀H₂₇N₅O₂
분자량:489.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CDD-1281 Chemical Structure

CAS No.: 3034215-91-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

CDD-1281 is a highly potent and selective BMPR2 kinase inhibitor with an IC₅₀ of 1.2 nM. CDD-1281 can effectively inhibit BMP-mediated gene expression^[1].

All TGF-β Receptor Isoforms :

Chemical Information

CAS No. 3034215-91-0
분자량 489.57
화학식 C₃₀H₂₇N₅O₂
SMILES

O=C(C1=CC=CC(CNC(C2=CC3=C(N=C(N3C4CCCC4)C5=CC6=C(C=NC=C6)C=C5)C=C2)=O)=C1)N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Feb 9;66(3):2143-2160. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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CDD-1281

All TGF-β Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CDD-1281 Related Classifications

HY-171247 Related Classifications