Cellohexaose
Based on 1 Customer Validation
Cellohexaose is a YKL-40 carbohydrate-binding ligand that occupies the primary carbohydrate-binding cleft through carbohydrate-π stacking and hydrogen-bonding interactions, and can serve as a bioinert spacer for hybrid glyco-nanolayers, modulating the surface density of bioactive shell hexaose to enhance TLR2-mediated responses. Cellohexaose is used in research on chronic inflammatory diseases and cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.95%
- CAS No.: 2478-35-5
- 화학식: C36H62O31
- 분자량:990.86
-
보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
In Vitro
Cellohexaose (300 K; 0.1-250 ns) binds to the main binding cleft of YKL-40, with an absolute free energy of -12.6 kJ/mol[1].
Cellohexaose (1.0 mM) interacts with the Au surface via S-Au coordination bonds, achieving a surface density of 0.811 chains nm-2[6].
Cellohexaose (1.0 mM; 24 h) forms a stable self-assembled monolayer on the Au surface[6].
Cellohexaose (1.0 × 105 cells mL-1; 3-120 h) supports the tight adhesion and 2-D proliferation of HepG2 cells, with the growth rate declining after 72 h[6].
Cellohexaose (1 mM; 3 days) supports lower CYP1A1 activity in HepG2 cells than the mixed nanolayer[6].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
-
Cell Line:HepG2
-
Concentration:1.0 × 105 cells mL-1
-
Incubation Time:3, 24, 72 and 120 h
-
Result:Proliferated well for 72 h after cell seeding, then growth rates decreased.
After 5 days, exhibited a 2-D form similar to cells on the TCPS plate.
Chemical Information
-
CAS No. 2478-35-5
-
Appearance Solid
-
분자량 990.86
-
화학식 C36H62O31
-
Color White to off-white
-
SMILES
O[C@H]1[C@]([C@H](O[C@@H](O[C@]([C@@H]2O)([H])[C@H](O[C@@H](O[C@@]([C@H](O)CO)([H])[C@H](O)[C@@H](O)C=O)[C@@H]2O)CO)[C@@H]1O)CO)([H])O[C@@H]([C@@H]([C@@H](O)[C@@H]3O[C@]([C@@H]([C@@H](O)[C@@H]4O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)O)([H])O[C@@H]4CO)O)O[C@@H]3CO
-
Structure Classification
-
Initial Source
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
-
Data Sheet (285 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cellohexaose Related Classifications
HY-N1915 Related Classifications
Powered by Bioz