CHMFL-KIT-031
CHMFL-KIT-031 is a highly selective KIT V559D inhibitor, with an IC50 of 28 nM. CHMFL-KIT-031 potently affects KIT V559D mutant’s phosphorylation at Y703/719/823 sites. CHMFL-KIT-031 inhibits the tumor growth in BaF3-TEL-KIT-V559D cell inoculated mouse model.
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- 화학식: C26H25N5O5
- 분자량:487.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
IC50: 28 nM (KIT V559D); 168 nM (KIT wt)[1].
Chemical Information
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분자량 487.51
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화학식 C26H25N5O5
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SMILES
O=C(NCC(NC1=CC2=C(C=C1)C(/C=C/C3=NC=CC=C3)=NN2)=O)C4=CC(OC)=C(OC)C(OC)=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CHMFL-KIT-031 Related Classifications
HY-122849 Related Classifications
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