Clamikalant
Clamikalant (HMR 1098 free base) is a compound used to suppress cardiac arrhythmias. It prevents the reduction of the refractory period during ventricular fibrillation in dogs and also shows antiarrhythmic effects in a rabbit heart model.
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- CAS No.: 158751-64-5
- 화학식: C19H22ClN3O5S2
- 분자량:471.98
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
8.2 μM
Compound: 33 HMR-1883
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Inhibition of human SUR1/Kir6.2 expressed in CHO cells
Inhibition of human SUR1/Kir6.2 expressed in CHO cells
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[PMID: 11356099] |
| Oocyte | IC50 |
4.3 μM
Compound: 33 HMR-1883
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Inhibition of human SUR2A/Kir6.2 expressed in Xenopus oocytes
Inhibition of human SUR2A/Kir6.2 expressed in Xenopus oocytes
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[PMID: 11356099] |
Chemical Information
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CAS No. 158751-64-5
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분자량 471.98
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화학식 C19H22ClN3O5S2
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SMILES
O=C(NCCC1=CC=C(OC)C(S(=O)(NC(NC)=S)=O)=C1)C2=CC(Cl)=CC=C2OC
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Synonyms
HMR 1098 free base
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clamikalant Related Classifications
HY-15208A Related Classifications
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