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Cat. No.: HY-N14422

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Collismycin B

Collismycin B is a potent dexamethasone-glucocorticoid receptor inhibitor with an IC₅₀ value of 10 µM. Collismycin B shows antimicrobial activity. Collismycin B shows cytotoxicity.

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CAS No.: 158792-25-7
화학식: C₁₃H₁₃N₃O₂S
분자량:275.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Collismycin B Chemical Structure

CAS No.: 158792-25-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Collismycin B is a potent dexamethasone-glucocorticoid receptor inhibitor with an IC₅₀ value of 10 µM. Collismycin B shows antimicrobial activity. Collismycin B shows cytotoxicity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	107 μM Compound: 4, SF2738B	Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation	[PMID: 21873059]

Chemical Information

CAS No. 158792-25-7
분자량 275.33
화학식 C₁₃H₁₃N₃O₂S
SMILES

O/N=C\C1=NC(C2=CC=CC=N2)=CC(OC)=C1SC
Structure Classification
- Alkaloids
- Pyridine Alkaloids
Initial Source
- Microorganisms
Streptomyces sp. MC025
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shindo K, et al. Collismycins A and B, novel non-steroidal inhibitors of dexamethasone-glucocorticoid receptor binding. J Antibiot (Tokyo). 1994 Sep;47(9):1072-4. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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