Coumestan
Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol (HY-N2335), Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective.
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- CAS No.: 479-12-9
- 화학식: C15H8O3
- 분자량:236.22
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 479-12-9
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분자량 236.22
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화학식 C15H8O3
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SMILES
O=C1C2=C(C3=C(O1)C=CC=C3)OC4=C2C=CC=C4
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Tabbasum MT, R S. Emerging Coumestans in Cancer Therapy With Mechanistic Insights and Clinical Potential. Arch Pharm (Weinheim). 2025 Jul;358(7):e70058. doi: 10.1002/ardp.70058. [Content Brief]
[2]. Kim JE, et al. Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor. Int J Mol Sci. 2017 Oct 24;18(10):2228. [Content Brief]
[3]. Lun S, et al. Therapeutic potential of coumestan Pks13 inhibitors for tuberculosis. Antimicrob Agents Chemother. 2023 May 1;95(5):e02190-20. [Content Brief]
[4]. Seong SH, et al. Phytoestrogen Coumestrol Selectively Inhibits Monoamine Oxidase-A and Amyloid β Self-Aggregation. Nutrients. 2022 Sep 16;14(18):3822. [Content Brief]
[5]. Djafarou S, Boulebd H. The radical scavenger capacity and mechanism of prenylated coumestan-type compounds: a DFT analysis. Free Radic Res. 2022 Mar-Apr;56(3-4):273-281. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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