Curcumin monoglucuronide
Curcumin monoglucuronide is known as a glucuronic acid conjugate, which is one of the in vivo metabolites of curcumin. Curcumin monoglucuronide is used for research on the metabolism of curcumin and examination of its development as a pharmaceutical. Curcumin monoglucuronide has the potential for the research of cancer disease (extracted from patent WO2022004873A1).
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- CAS No.: 2171091-50-0
- 화학식: C27H28O12
- 분자량:544.50
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>200 μM
Compound: 2
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 24280069] |
| Jurkat | IC50 |
>200 μM
Compound: 2
|
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 24280069] |
| KBM5 | IC50 |
>200 μM
Compound: 2
|
Antiproliferative activity against human KBM5 cells after 72 hrs by MTT assay
Antiproliferative activity against human KBM5 cells after 72 hrs by MTT assay
|
[PMID: 24280069] |
| U-266 | IC50 |
>200 μM
Compound: 2
|
Antiproliferative activity against human U266 cells after 72 hrs by MTT assay
Antiproliferative activity against human U266 cells after 72 hrs by MTT assay
|
[PMID: 24280069] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 2171091-50-0
-
분자량 544.50
-
화학식 C27H28O12
-
SMILES
COC(C=C(C=C1)/C=C/C(/C=C(O)/C=C/C2=CC(OC)=C(C=C2)O)=O)=C1O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O
-
Synonyms
CMG
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)