CW2158
CW2158 (Compound 13) is a modulator for exportin1 (XPO1) ,which disrupts the chromatin binding, inhibits NFAT transcription factors and activation of T cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C14H8F4N4O2
- 분자량:340.23
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
CW2158 (10 nM-10 μM) inhibits the expression of IL-2 (6 h) and viability (24 h) of Jurkat cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Jurkat
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Concentration:10 nM-10 μM
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Incubation Time:24 h
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Result:Inhibited cell viability of Jurkats.
Chemical Information
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분자량 340.23
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화학식 C14H8F4N4O2
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SMILES
FC(F)(F)C(N=C1NN2C(C=C(C)C2=O)=O)=NC3=C1C(F)=CC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CW2158 Related Classifications
HY-161392 Related Classifications
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