DB772 free base
Based on 1 publication(s) in Google Scholar
DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity.
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- CAS No.: 433735-90-1
- 화학식: C20H16N4O
- 분자량:328.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Publications Citing Use of MedChemExpress (MCE) DB772 free base
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
8.6 μM
Compound: DB772
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Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation
Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation
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[PMID: 11985467] |
Chemical Information
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CAS No. 433735-90-1
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분자량 328.37
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화학식 C20H16N4O
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SMILES
C1(N=C(C2=CC=C(C3=CC=C(C4=NCCN4)C=C3)O2)N5)=C5C=CC=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
순도&문서
References
[1]. James B Stanton, et al. Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells. PLoS One. 2012;7(11):e51173. [Content Brief]
[2]. Benjamin W Newcomer, et al. Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species. Antiviral Res. 2012 Nov;96(2):127-9. [Content Brief]
[3]. Kelcey D Dinkel, et al. Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5467-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DB772 free base Related Classifications
HY-114621B Related Classifications
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