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Cat. No.: HY-B0632S2

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Diltiazem-d₄

Diltiazem-d₄ is the deuterated-labeled Diltiazem (HY-B0632). Diltiazem is a calcium antagonist and an L-type calcium channel inhibitor. Diltiazem inhibits Ca²⁺ mobilization/influx, norepinephrine-induced contraction, and depolarization. Diltiazem produces coronary vasodilation and renal vasodilation; it inhibits sodium reabsorption in the distal nephron and increases urine flow, sodium and potassium excretion, Inulin (HY-N7075) and PAH clearance, and free water clearance. Diltiazem is used in research on cardiovascular diseases, kidney diseases, and inflammation.

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CAS No.: 112259-41-3
화학식: C₂₂H₂₂D₄N₂O₄S
분자량:418.54

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Diltiazem-d₄ Chemical Structure

CAS No.: 112259-41-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- 신청
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[4]

L-type calcium channel

All Calcium Channel Isoforms :

신청

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 112259-41-3
Unlabeled CAS 42399-41-7
분자량 418.54
화학식 C₂₂H₂₂D₄N₂O₄S
SMILES

CC(O[C@@H]1[C@H](C2=CC=C(C=C2)OC)SC3=CC=CC=C3N(C1=O)C([2H])([2H])C([2H])([2H])N(C)C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nagao T, et al. Studies on a New 1,5-Benzothiazepine Derivative (CRD-401). IV. Coronary Vasodilating Effect and Structure-Activity Relationship. Chemical and Pharmaceutical Bulletin, 1973, 21(1): 92-97.

[2]. Yamaguchi I, et al. Studies on a New 1,5-Benzothiazepine Derivative (CRD-401): VI. Effects on Renal Blood Flow and Renal Function. Japanese Journal of Pharmacology, 1974, 24(4): 511-522.

[3]. Ito Y, et al. The effects of diltiazem (CRD-401) on the membrane and mechanical properties of vascular smooth muscles of the rabbit. British journal of pharmacology. 1978 Dec;64(4):503-10. [Content Brief]

[4]. Mieth A, et al. L-type calcium channel inhibitor diltiazem prevents aneurysm formation by blood pressure-independent anti-inflammatory effects. Hypertension. 2013 Dec;62(6):1098-104. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- 신청
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
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Diltiazem-d4

All Calcium Channel Isoforms

Biological Activity

제품 설명

IC50 & Target

신청

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Diltiazem-d4 Related Classifications

HY-B0632S2 Related Classifications

Bioz

Keywords

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