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Cat. No.: HY-111761

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DIQ3

DIQ3 is a potent anti-cancer agent, nontoxic to normal human cell lines.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2258636-02-9
화학식: C₂₃H₁₅N₅
분자량:361.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

DIQ3 Chemical Structure

CAS No.: 2258636-02-9

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

DIQ3 is a potent anti-cancer agent, nontoxic to normal human cell lines^[1].

In Vitro

DIQ3 (3-10 μM) reduces cell viability of HCT116 cell line after treatment for 24, 48 and 72 h; while it shows no effect at 1-2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

HCT116 cell lines
Concentration:

1-10 μM
Incubation Time:

24, 48 and 72 hours
Result:

Inhibited cell viability by approximately more than 50% at 24 h at as low as 4 μM.

Chemical Information

CAS No. 2258636-02-9
분자량 361.40
화학식 C₂₃H₁₅N₅
SMILES

N=C1N=C2N(CC3=C(C#N)C=CC=C3)C4=CC=CC=C4N=C2C5=C1C=CC=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Monzer A, et al. Novel 2-(5-Imino-5H-isoquinolones[3,4-b]quinoxalin-7-ylmethyl)-benzonitrile (DIQ3) and Other Related Derivatives Targeting Colon Cancer Cells: Syntheses and in Vitro Models. ACS Omega. 2019 Feb 28;4(2):3205-3212. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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