DLRIE
Based on 1 Customer Validation
DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids.
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- Purity: 99.41%
- CAS No.: 199171-54-5
- 화학식: C31H66BrNO3
- 분자량:580.76
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 199171-54-5
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Appearance Solid
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분자량 580.76
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화학식 C31H66BrNO3
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Color White to off-white
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SMILES
OCC[N+](C)(CC(COCCCCCCCCCCCC)OCCCCCCCCCCCC)C.[Br-]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 100 mg/mL (172.19 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Wheeler CJ, et al. A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11454-9. [Content Brief]
[2]. Felgner PL, et al. Improved cationic lipid formulations for in vivo gene therapy. Ann N Y Acad Sci. 1995 Nov 27;772:126-39. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7219 mL | 8.6094 mL | 17.2188 mL | 43.0470 mL |
| 5 mM | 0.3444 mL | 1.7219 mL | 3.4438 mL | 8.6094 mL | |
| 10 mM | 0.1722 mL | 0.8609 mL | 1.7219 mL | 4.3047 mL | |
| 15 mM | 0.1148 mL | 0.5740 mL | 1.1479 mL | 2.8698 mL | |
| 20 mM | 0.0861 mL | 0.4305 mL | 0.8609 mL | 2.1524 mL | |
| 25 mM | 0.0689 mL | 0.3444 mL | 0.6888 mL | 1.7219 mL | |
| 30 mM | 0.0574 mL | 0.2870 mL | 0.5740 mL | 1.4349 mL | |
| 40 mM | 0.0430 mL | 0.2152 mL | 0.4305 mL | 1.0762 mL | |
| 50 mM | 0.0344 mL | 0.1722 mL | 0.3444 mL | 0.8609 mL | |
| 60 mM | 0.0287 mL | 0.1435 mL | 0.2870 mL | 0.7175 mL | |
| 80 mM | 0.0215 mL | 0.1076 mL | 0.2152 mL | 0.5381 mL | |
| 100 mM | 0.0172 mL | 0.0861 mL | 0.1722 mL | 0.4305 mL |