country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187410A

Copy Link Print Information

DOPE-PEG2000-APRPG

(Synonyms: DOPE-PEG2000-Mal-Cys-APRPG)

DOPE-PEG2000-APRPG (DOPE-PEG2000-Mal-Cys-APRPG) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the APRPG peptide (Ala-Pro-Arg-Gly), a tumor-homing peptide. DOPE-PEG2000-APRPG is used for tumor vasculature-targeted drug delivery.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

DOPE-PEG2000-APRPG Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

DOPE-PEG2000-APRPG: surface modification of liposomes and nanoparticles for tumor vasculature-targeted drug delivery and anti-angiogenic research in cancer treatment.
Structural composition:
(1) DOPE; a fusogenic phospholipid with two oleoyl chains that anchors into lipid bilayers and promotes pH-dependent membrane fusion for intracellular drug release;
(2) PEG2000; a hydrophilic polymer that provides steric stabilization, reduces opsonization and immune clearance, and extends blood circulation half-life;
(3) APRPG peptide; a tumor-homing tetrapeptide that specifically binds to aminopeptidase N (CD13), a cell-surface enzyme highly expressed on angiogenic endothelial cells in tumor vasculature but not on normal blood vessels, enabling selective targeting of tumor neovasculature for anti-angiogenic drug delivery.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

[DOPE-PEG2000-APRPG]
Synonyms

DOPE-PEG2000-Mal-Cys-APRPG
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.