country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-121582

Copy Link Print Information

(E)-SI-2

Name: (E)-SI-2
Brand: MedChemExpress
SKU: HY-121582
Price: 159.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (E)-EPH 116)

(E)-SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 380537-35-9
화학식: C₁₅H₁₅N₅
분자량:265.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(E)-SI-2 Chemical Structure

CAS No.: 380537-35-9

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

(E)-SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer^[1].

IC₅₀ & Target

SRC-3^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
TOV112D	EC₅₀	0.004 μM Compound: C9	Growth inhibition of human TOV112D cells harbouring p53 R175H mutant incubated for 3 days by MTS assay Growth inhibition of human TOV112D cells harbouring p53 R175H mutant incubated for 3 days by MTS assay	[PMID: 33538587]

Chemical Information

CAS No. 380537-35-9
분자량 265.31
화학식 C₁₅H₁₅N₅
SMILES

CN1C2=CC=CC=C2N=C1N/N=C(C3=CC=CC=N3)\C
Synonyms

(E)-EPH 116
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Han SJ, et al. Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment. Breast Cancer Res. 2022 Oct 31;24(1):73. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

(E)-SI-2

KL001

KL001 (Standard)

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

(E)-SI-2

KL001

KL001 (Standard)

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(E)-SI-2 Related Classifications

HY-121582 Related Classifications

Bioz