Effusanin B
Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity.
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- CAS No.: 76470-16-1
- 화학식: C22H30O6
- 분자량:390.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
3.5 μM
Compound: 15
|
Cytotoxicity against human A549 cells after 48 hrs by MTT method
Cytotoxicity against human A549 cells after 48 hrs by MTT method
|
[PMID: 21534539] |
| Bel-7402 | IC50 |
7.3 μM
Compound: 18
|
Cytotoxicity against human Bel7402 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Bel7402 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 20949916] |
| HL-60 | IC50 |
0.7 μM
Compound: 15
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT method
Cytotoxicity against human HL60 cells after 48 hrs by MTT method
|
[PMID: 21534539] |
| HT-29 | IC50 |
4.1 μM
Compound: 18
|
Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 20949916] |
| MCF7 | IC50 |
0.7 μM
Compound: 15
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT method
Cytotoxicity against human MCF7 cells after 48 hrs by MTT method
|
[PMID: 21534539] |
| SK-OV-3 | IC50 |
2.1 μM
Compound: 18
|
Cytotoxicity against human SKOV3 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human SKOV3 cells after 72 hrs by sulforhodamine B assay
|
[PMID: 20949916] |
| SMMC-7721 | IC50 |
1 μM
Compound: 15
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT method
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT method
|
[PMID: 21534539] |
| SW480 | IC50 |
0.8 μM
Compound: 15
|
Cytotoxicity against human SW480 cells after 48 hrs by MTT method
Cytotoxicity against human SW480 cells after 48 hrs by MTT method
|
[PMID: 21534539] |
Effusanin B (Compound 3) exhibits significant cytotoxic activity against DNA repair-deficient (RAD 52Y, mutant) yeast strains[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 76470-16-1
-
분자량 390.47
-
화학식 C22H30O6
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SMILES
CC(O[C@@H]1[C@@]23[C@@]4([H])[C@]5(C[C@@](C(C5=O)=C)([H])CC4)[C@@]([C@H]([C@]2([H])C(C)(CC1)C)O)(OC3)O)=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)