Episterol
Episterol is an Ergosterol (HY-N0181) biosynthetic intermediate. Episterol replaces Ergosterol as the major sterol in Saccharomyces cerevisiae Δerg3 mutants, confers resistance to combined lethal and vacuole-disruptive actions of Amphotericin B (HY-B0221) and MC12 (HY-175024).
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- CAS No.: 474-68-0
- 화학식: C28H46O
- 분자량:398.68
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
In Vitro
Episterol accumulation in Saccharomyces cerevisiae Δerg3 mutant cells eliminates the synergistic antifungal activity between Amphotericin B (HY-B0221) and MC12 (HY-175024), resulting in an indifferent drug interaction with an FIC index of 2.00[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 474-68-0
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분자량 398.68
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화학식 C28H46O
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SMILES
C[C@@]12[C@](C=3[C@@]([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])(CC1)[H])(CC[C@@]2([C@@H](CCC(C(C)C)=C)C)[H])[H]
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Structure Classification
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Initial Source
Saccharomyces cerevisiae
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)