Exatecan Intermediate 4
Based on 1 Customer Validation
Exatecan Intermediate 4 (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers.
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- Purity: 98.95%
- CAS No.: 2436720-50-0
- 화학식: C11H14ClFN2O
- 분자량:244.70
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보관:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
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Camptothecins |
Camptothecin derivatives are a class of cytotoxic small molecules that can be used in the preparation of antibody-drug conjugates. Camptothecin derivatives generally exhibit antitumor effects by inhibiting topoisomerase I[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2436720-50-0
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Appearance Solid
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분자량 244.70
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화학식 C11H14ClFN2O
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SMILES
CC1=C2CCC(C(C2=C(C=C1F)N)=O)N.Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
순도&문서
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)