EXEL-0346
EXEL-0346 is an orally active glucosylceramide synthase (GCS) inhibitor, with an IC50 of 2 nM. EXEL-0346 combined with insulin increases pAkt. EXEL-0346 effectively reduces the levels of Glucosylceramide, Lactosylceramide and GM3. EXEL-0346 improves obesity and diabetes.
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- CAS No.: 1239893-96-9
- 화학식: C27H29BrF3N3O3
- 분자량:580.44
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
IC50: 2 nM (GCS)[1]
Chemical Information
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CAS No. 1239893-96-9
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분자량 580.44
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화학식 C27H29BrF3N3O3
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SMILES
O=C(C1(C2=CC=C(OC(F)(F)F)C=C2)CC1)N[C@@H](CC3=CC=C(Br)C=C3)C(N4C5CC(N)CC4CC5)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EXEL-0346 Related Classifications
HY-112488 Related Classifications
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