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Cat. No.: HY-128685

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FD 12-9

(Synonyms: Ac12Az9)

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC₅₀s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity.

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CAS No.: 1451741-22-2
화학식: C₅₁H₄₇N₃O₁₁
분자량:877.93

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

FD 12-9 Chemical Structure

CAS No.: 1451741-22-2

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가격

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC₅₀s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity^[1].

IC₅₀ & Target

EC50: 0.9 nM (BCRP), 285 nM (P-gp)^[1]

Chemical Information

CAS No. 1451741-22-2
분자량 877.93
화학식 C₅₁H₄₇N₃O₁₁
SMILES

O=C(OC)C1=CC=CC(COC2=C(C3=CC=C(OCCOCCOCCN4N=NC(CCCCOC5=CC=C6C(C=C(C7=CC=CC=C7)OC6=C5)=O)=C4)C=C3)OC8=CC=CC=C8C2=O)=C1
Synonyms

Ac12Az9
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hu Xuesen, et al. Developing a novel strategy to treat glioblastoma : improving brain bioavailability of sorafenib with a synthetic flavonoid dimer to inhibit drug efflux in blood brain barrier.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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FD 12-9

Elacridar

Tariquidar

Zosuquidar

Elacridar (Standard)

Tariquidar methanesulfonate, hydrate

KS176

Elacridar hydrochloride

YHO-13177

Tariquidar (Standard)

Reversan

Ko 143

YHO-13351 free base

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

FD 12-9

Elacridar

Tariquidar

Zosuquidar

Elacridar (Standard)

Tariquidar methanesulfonate, hydrate

KS176

Elacridar hydrochloride

YHO-13177

Tariquidar (Standard)

Reversan

Ko 143

YHO-13351 free base

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

FD 12-9 Related Classifications

HY-128685 Related Classifications