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Frenlosirsen

(Synonyms: ION-935918; ION251)
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Frenlosirsen (ION-935918; ION251) is an antisense oligonucleotide and also an IRF4 inhibitor. Frenlosirsen inhibits the survival of malignant plasma cells, reduces the burden of myeloma progenitor cells and prevents disease recurrence. Frenlosirsen is applicable to myeloma-related research.

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  • Purity: 96.46%
  • CAS No.: 2304711-81-5
  • 화학식: C177H226N63O89P15S15
  • 분자량:5605.63
  • 보관:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Frenlosirsen Chemical Structure
    Frenlosirsen Chemical Structure
CAS No.: 2304711-81-5
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  • Frenlosirsen Chemical Structure
    Frenlosirsen Chemical Structure DNA, d(P-thio)([2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]A-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]G-T-T-G-T-A-A-A-T-G-[2'-O-(2-methoxyethyl)]rA[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]m5rU-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]m5C-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]G)
    1/16
  • DNA, d(P-thio)([2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]A-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]G-T-T-G-T-A-A-A-T-G-[2'-O-(2-methoxyethyl)]rA[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]m5rU-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]m5C-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-l-mannofurano]G)