Ganfeborole
Based on 5 publication(s) in Google Scholar
Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2131798-12-2
- 화학식: C10H13BClNO4
- 분자량:257.48
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Ganfeborole
More
Biological Activity
제품 설명
Chemical Information
-
CAS No. 2131798-12-2
-
분자량 257.48
-
화학식 C10H13BClNO4
-
SMILES
OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21
-
Synonyms
GSK656 free base; GSK3036656 free base; GSK070 free base
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
-
Journal Impact Factor
-
Most Recent
-
Nat Nanotechnol
Nanofibrous supramolecular peptide hydrogels for controlled release of small-molecule drugs and biologics. [Abstract]2025 Oct;20(10):1502-1513. PMID: 40931056 -
Antimicrob Agents Chemother
A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo. [Abstract]2022 Sep 20;66(9):e0060122. PMID: 35969055 -
-
ACS Chem Biol
Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. [Abstract]2022 Jan 21;17(1):39-53. PMID: 34908399 -
Protocol
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)