Btg2 - BTG anti-proliferation factor 2 Gene

Also Known as An; Agl; Pc3; an-1; Tis21

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29619

Summary

Enables transcription corepressor activity. Involved in several processes, including negative regulation of neuron apoptotic process; response to electrical stimulus; and response to peptide hormone. Acts upstream of or within negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; and neuron differentiation. Predicted to be active in cytoplasm and nucleus. Biomarker of acute necrotizing pancreatitis and brain ischemia. Orthologous to human BTG2 (BTG anti-proliferation factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Btg2 Products (1)

mRNA Protein Name
NM_017259.2 NP_058955.1 protein BTG2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11237868 RGD
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
20020054 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to phorbol 13-acetate 12-myristate IEP
IEP: Inferred from expression pattern
2005087 RGD
acts upstream of or within negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
12360398 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
12360398 RGD
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
20020054 RGD
acts upstream of or within neuron differentiation IDA
IDA: Inferred from direct assay
12360398 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
23000394 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
8879470 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
15519684 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
8263025 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein BTG2

  • B-cell translocation gene 2, anti-proliferative

  • BTG family, member 2

  • Early induced gene B-cell translocation gene 2

  • NGF-inducible anti-proliferative protein PC3

  • NGF-inducible anti-proliferative putative secreted protein

  • cell surface alloantigen

Btg2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Btg2 P27049 Pick1 Rattus norvegicus Q9EP80
Pull Down
11237868
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-113455 9(S)-HODE Inducer 98.0% Unkown
HY-RS01663 BTG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20698 Btg2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27209 Btg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Btg2 NCBI NCBI:7832