RPS25 - ribosomal protein S25 Gene
Also Known as S25
Species: Homo sapiens
About RPS25
This gene has 6 transcripts (splice variants), 1 gene allele and 201 orthologues. Ubiquitous expression in ovary (RPKM 1368.6), lymph node (RPKM 772.3) and 25 other tissues.
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
RPS25 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001028.3 | NP_001019.1 | 40S ribosomal protein S25 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
22720776 | GOA |
| enables structural constituent of ribosome |
IDA
IDA: Inferred from direct assay
|
23636399 | GOA |
| enables structural constituent of ribosome |
IMP
IMP: Inferred from mutant phenotype
|
18697920 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in rRNA processing |
IMP
IMP: Inferred from mutant phenotype
|
18697920 | GOA |
| involved in ribosomal small subunit biogenesis |
IMP
IMP: Inferred from mutant phenotype
|
18697920 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytosolic ribosome |
IDA
IDA: Inferred from direct assay
|
23636399 | GOA |
| part of cytosolic small ribosomal subunit |
IDA
IDA: Inferred from direct assay
|
8706699 | GOA |
| located in nucleolus |
IDA
IDA: Inferred from direct assay
|
10050887 | GOA |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
22720776 | GOA |
| is active in postsynaptic density |
EXP
EXP: Inferred from Experiment
|
21170055 | GOA |
| is active in postsynaptic density |
IDA
IDA: Inferred from direct assay
|
21170055 | GOA |
| located in ribosome |
IDA
IDA: Inferred from direct assay
|
1748303 | GOA |
RPS25 Protein Structure
Ribosomal_S25: S25 ribosomal protein (1 - 113)
- 0
- 100
- 125 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
40S ribosomal protein S25 |
|
RPS25 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
RPS25 | P62851 | ZBTB14 | Homo sapiens | O43829 | 32296183 | |
|
Intra
|
RPS25 | P62851 | ZBTB14 | Homo sapiens | O43829 | 32296183 | |
|
Intra
|
RPS25 | P62851 | HMBOX1 | Homo sapiens | Q6NT76 | 32296183 | |
|
Intra
|
RPS25 | P62851 | HMBOX1 | Homo sapiens | Q6NT76 | 32296183 | |
|
Intra
|
RPS25 | P62851 | HMBOX1 | Homo sapiens | Q6NT76 | 32296183 | |
|
Intra
|
RPS25 | P62851 | NKAPD1 | Homo sapiens | Q6ZUT1 | 32296183 | |
|
Intra
|
RPS25 | P62851 | THAP1 | Homo sapiens | Q9NVV9 | 25416956 | |
|
Intra
|
RPS25 | P62851 | THAP1 | Homo sapiens | Q9NVV9 | 25416956 | |
|
Intra
|
RPS25 | P62851 | STAC3 | Homo sapiens | Q96MF2 | 32296183 | |
|
Intra
|
RPS25 | P62851 | STAC3 | Homo sapiens | Q96MF2 | 32296183 | |
|
Intra
|
RPS25 | P62851 | STAC3 | Homo sapiens | Q96MF2 | 32296183 | |
|
Intra
|
RPS25 | P62851 | TSPYL2 | Homo sapiens | Q9H2G4 | 32296183 | |
|
Intra
|
RPS25 | P62851 | TSPYL2 | Homo sapiens | Q9H2G4 | 32296183 | |
|
Intra
|
RPS25 | P62851 | TSPYL2 | Homo sapiens | Q9H2G4 | 32296183 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Chromosome 5q Deletion Syndrome |
|
|
| Diamond-Blackfan Anemia |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | RPS25 | RGD | RGD:621043 |
| Mus musculus | RPS25 | MGD | MGI:1922867 |
| Others | RPS25 | NCBI |