GMBS
Based on 1 Customer Validation
GMBS is a heterobifunctional crosslinker targeting primary amines and sulfhydryl groups. GMBS can be used for chemical crosslinking of proteins and crosslinking mass spectrometry (CXMS) to study protein folding and map interfaces between interacting proteins.
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- Purity: 99.66%
- CAS No.: 80307-12-6
- 화학식: C12H12N2O6
- 분자량:280.23
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보관:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
GMBS generates non-redundant and structurally compatible cross-links in BSA, aldolase, and yeast CNG protein subcomplexes[1].
GMBS generates a small amount of complementary cross-links in crude E. coli 70S ribosomes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 80307-12-6
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Appearance Solid
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분자량 280.23
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화학식 C12H12N2O6
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Color White to off-white
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SMILES
O=C(ON1C(CCC1=O)=O)CCCN2C(C=CC2=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
DMSO : 50 mg/mL (178.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5685 mL | 17.8425 mL | 35.6850 mL | 89.2124 mL |
| 5 mM | 0.7137 mL | 3.5685 mL | 7.1370 mL | 17.8425 mL | |
| 10 mM | 0.3568 mL | 1.7842 mL | 3.5685 mL | 8.9212 mL | |
| 15 mM | 0.2379 mL | 1.1895 mL | 2.3790 mL | 5.9475 mL | |
| 20 mM | 0.1784 mL | 0.8921 mL | 1.7842 mL | 4.4606 mL | |
| 25 mM | 0.1427 mL | 0.7137 mL | 1.4274 mL | 3.5685 mL | |
| 30 mM | 0.1189 mL | 0.5947 mL | 1.1895 mL | 2.9737 mL | |
| 40 mM | 0.0892 mL | 0.4461 mL | 0.8921 mL | 2.2303 mL | |
| 50 mM | 0.0714 mL | 0.3568 mL | 0.7137 mL | 1.7842 mL | |
| 60 mM | 0.0595 mL | 0.2974 mL | 0.5947 mL | 1.4869 mL | |
| 80 mM | 0.0446 mL | 0.2230 mL | 0.4461 mL | 1.1152 mL | |
| 100 mM | 0.0357 mL | 0.1784 mL | 0.3568 mL | 0.8921 mL |