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Cat. No.: HY-N15587

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Gostatin

(Synonyms: Gostatine)

Gostatin is an inhibitor of aspartate aminotransferase (GOT). Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism.

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CAS No.: 78416-84-9
화학식: C₈H₁₀N₂O₅
분자량:214.18

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Gostatin Chemical Structure

CAS No.: 78416-84-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Aminotransferases (Transaminases) Isoforms :

Chemical Information

CAS No. 78416-84-9
분자량 214.18
화학식 C₈H₁₀N₂O₅
SMILES

OC(CC1=C(NCC(C1=O)N)C(O)=O)=O
Synonyms

Gostatine
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Streptomyces sumanensis nov. sp.
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sawao Murao, et al. New Aspartate Aminotransferase Inhibitor (Gostatin) Produced by Streptomyces sumanensis nov. sp., NK-23. Agricultural and Biological Chemistry, Volume 45, Issue 4, 1 April 1981, Pages 1039–1041.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Gostatin

All Aminotransferases (Transaminases) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Gostatin Related Classifications

HY-N15587 Related Classifications