hAChE-IN-9
hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE) with IC50 of 0.05 μM and 2.85 μM for AChE and BChE, respectively. hAChE-IN-9 modulates toxic Aβ oligomer forms into non-toxic ones and has antioxidant and neuroprotective effects against Aβ-induced toxicity. hAChE-IN-9 can be used for the study of Alzheimer's disease.
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- 화학식: C20H15ClN6O4S
- 분자량:470.89
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
hAChE 0.05 μM (IC50) |
hBCHE 2.85 μM (IC50) |
Chemical Information
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분자량 470.89
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화학식 C20H15ClN6O4S
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SMILES
O=C(/C(C#N)=C(SC)/NC1=CC=C([N+]([O-])=O)C=C1)NN2C(CCl)=NC3=CC=CC=C3C2=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hAChE-IN-9 Related Classifications
HY-168052 Related Classifications
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