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Cat. No.: HY-155410

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HPSE1-IN-1

HPSE1-IN-1 (compound 16) is a selective inhibitor of Heparanase-1 (HPSE1) with moderate inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA).

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CAS No.: 2876926-29-1
화학식: C₃₀H₃₀N₂O₆
분자량:514.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

HPSE1-IN-1 Chemical Structure

CAS No.: 2876926-29-1

사이즈

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재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

HPSE1-IN-1 (compound 16) is a selective inhibitor of Heparanase-1 (HPSE1) with moderate inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)^[1].

IC₅₀ & Target

Heparanase-1 (HPSE1), exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)^[1]

All Endogenous Metabolite Isoforms :

Chemical Information

CAS No. 2876926-29-1
분자량 514.57
화학식 C₃₀H₃₀N₂O₆
SMILES

OC([C@H]1N2C([C@@H]([C@H]([C@@H]1OCCC3=CC=CC=C3)O)O)=NC(CCC4=CC(OC5=CC=CC=C5)=CC=C4)=C2)=O
Structure Classification
- Others
Initial Source
- Endogenous metabolite
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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HPSE1-IN-1

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

HPSE1-IN-1 Related Classifications

HY-155410 Related Classifications