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Cat. No.: HY-N9826

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Icterogenin

Icterogenin is a selective inhibitor targeting the Bcl-XL/Bak BH3 domain peptide interaction and exhibits anti-leukemic activity. Icterogenin regulates protein interactions and affects tumor cell survival. Icterogenin is an oleanane-type triterpenoid compound that can be isolated from Lantana camara and is useful in the field of anti-tumor drug development.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 561-47-7
화학식: C₃₅H₅₂O₆
분자량:568.78

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Icterogenin Chemical Structure

CAS No.: 561-47-7

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

Bcl-xL

All Bcl-2 Family Isoforms :

In Vitro

Icterogenin exhibits cytotoxicity against HL-60 human promyelocytic leukemia cells, with IC₅₀ values ranging from 1.16 to 68.4 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 561-47-7
분자량 568.78
화학식 C₃₅H₅₂O₆
SMILES

OC([C@@]([C@@H](C1)OC(/C(C)=C\C)=O)(CC[C@]23C)[C@](CC1(C)C)([H])C2=CC[C@@]4([H])[C@]3(CC[C@]([C@](C)5CO)([H])[C@@]4(CCC5=O)C)C)=O
Structure Classification
- Terpenoids
- Pentacyclic Triterpenoids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ono M, et al. Two new triterpenoids from the leaves and stems of Lantana camara. Nat Prod Res. 2021 Nov;35(21):3757-3765. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
수량:

Icterogenin

All Bcl-2 Family Isoforms