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Cat. No.: HY-189072

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Insecticidal agent 39

Insecticidal agent 39 (compound I ai) is a potent insecticide that targets Ryanodine Receptor (RyR). The LC₅₀ of Insecticidal agent 39 against M. separata is 0.26 mg/L. Insecticidal agent 39 specifically binds to and activates RyR, inducing the release of Ca²⁺ from the sarcoplasmic reticulum into the cytoplasm, which leads to sustained muscle contraction and eventual paralysis and death of the pest. Insecticidal agent 39 can be used in studies related to lepidopteran pest infestation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₄H₁₈BrCl₂N₃O₂
분자량:531.23

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Insecticidal agent 39 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Calcium Channel Isoforms :

In Vitro

Insecticidal agent 39 (compound I ai) binds to the Mythimna separata ryanodine receptor (MsRyR) with a binding energy of 8.1 kcal/mol. It shares the same binding pocket as Chlorantraniliprole (HY-112820) and forms key hydrogen bonds with ASP-4901 and LYS-4652^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Insecticidal agent 39 (compound I ai) (oral exposure via treated maize leaves, single administration) exhibits potent insecticidal activity against Mythimna separata, Plutella xylostella and Spodoptera frugiperda, with an LC₅₀ of 0.26 mg/L against Mythimna separata^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

분자량 531.23
화학식 C₂₄H₁₈BrCl₂N₃O₂
SMILES

ClC1=C(N2C(C=CC(Br)=C3)=C3C=C2C(NC4=C(C(NC)=O)C=C(Cl)C=C4C)=O)C=CC=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Duan J, et al. Discovery of Substituted N-Arylindole Diamides as Insecticidal Candidates Targeting Ryanodine Receptor. Journal of agricultural and food chemistry. 2026 Aug 12;74(31):24115-24123.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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