Kribb3
Kribb3 is an inhibitor for microtubule. KRIBB3 inhibits the proliferation of cancer cells with GI50 of 0.2-2.5 μM, arrests cell cycle at G2/M phase, and induces apoptosis in HCT-116. Kribb3 exhibits antitumor activity in mouse models.
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- CAS No.: 129414-88-6
- 화학식: C19H19NO4
- 분자량:325.36
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
0.15 μM
Compound: 46
|
Antimigratory activity against human MDA-MB-231 cells
Antimigratory activity against human MDA-MB-231 cells
|
[PMID: 28605676] |
Chemical Information
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CAS No. 129414-88-6
-
분자량 325.36
-
화학식 C19H19NO4
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SMILES
OC1=CC(OC)=C(C=C1C2=C(C=NO2)C3=CC=C(C=C3)OC)CC
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)