L-748328
L-748328 is a potent and selective human β3-adrenergic receptor antagonist. L-748328 has a Ki of 3.7 nM against human cloned β3-AR expressed in Chinese hamster ovary (CHO) cells. In addition, L-748328 inhibits the lipolytic response induced by the β3-AR agonist L-742791 in isolated non-human primate adipocytes.
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- CAS No.: 244192-93-6
- 화학식: C23H27N3O6S2
- 분자량:505.61
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
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β3 adrenoceptor 3.7 nM (Ki) |
Chemical Information
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CAS No. 244192-93-6
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분자량 505.61
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화학식 C23H27N3O6S2
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SMILES
O=S(C1=CC=CC(OC[C@H](CNCCC2=CC=C(C=C2)NS(=O)(C3=CC=CC=C3)=O)O)=C1)(N)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-748328 Related Classifications
HY-118944 Related Classifications
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