Lankacidinol
Lankacidinol (T-2636 F) is an antibiotic. Lankacidinol and its related metabolites 2,18-seco-lankacidinol A (1) and 2,18-seco-lankacidinol B (2) have significant biological activities and potential medicinal value. In addition, 2,18-seco-lankacidinol A exhibits potent antitumor activity.
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- CAS No.: 23498-37-5
- 화학식: C25H35NO7
- 분자량:461.55
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>100 μM
Compound: 3
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 34883453] |
| HeLa | IC50 |
24.8 μM
Compound: 3
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 34883453] |
| MCF7 | IC50 |
75.7 μM
Compound: 3
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 34883453] |
Chemical Information
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CAS No. 23498-37-5
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분자량 461.55
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화학식 C25H35NO7
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SMILES
O[C@@H](C(N[C@@H]([C@](C)1C([C@@H]2C)=O)/C=C(/C=C/[C@H](C/C=C(/C=C/[C@H](C[C@]2(OC1=O)[H])O)C)O)C)=O)C
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Synonyms
T-2636 F
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Initial Source
Streptomyces sp.
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)