LCB-2151
LCB-2151 (Compound 2), a nucleoside analogue, is an anticancer agent. LCB-2151 disrupts the two primary sources of ATP production (glycolysis and mitochondrial oxidative phosphorylation), reducing the bioenergetic capacity of KRAS-mutated pancreatic cancer cells and inducing ROS formation. LCB-2151 effectively inhibits key enzymes (such as CACT and CPT2) in glycolysis, the TCA cycle and fatty acid β-oxidation. LCB-2151 has significant cytotoxicity and induces cells apoptosis. LCB-2151 can be used for radiation therapy of cancers research.
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- CAS No.: 2211175-99-2
- 화학식: C37H43F8N3O5S2
- 분자량:825.87
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
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CPT-2 |
Chemical Information
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CAS No. 2211175-99-2
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분자량 825.87
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화학식 C37H43F8N3O5S2
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SMILES
OC[C@@]1(C)C(F)(F)[C@H](N2C(N=C(NC(CC(C)(C)CC[C@@H](SCC3=CC=C(C(F)(F)F)C=C3)CCSCC4=CC=C(C(F)(F)F)C=C4)=O)C=C2)=O)O[C@@H]1CO
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LCB-2151 Related Classifications
HY-175673 Related Classifications
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- LCB-2151
- 2211175-99-2
- LCB2151
- LCB 2151
- Carnitine Palmitoyltransferase (CPT)
- Apoptosis
- Oxidative Phosphorylation
- Mitochondrial Metabolism
- Reactive Oxygen Species (ROS)
- Nucleoside analogue
- Anticancer
- Glycolysis
- Mitochondrial
- Oxidative phosphorylation
- TCA cycle,Fatty acid β-oxidation
- Panc-1 cells
- Capan-2 cells
- HepG2 cells
- BxPC3 cells
- Radiation therapy
- Inhibitor
- inhibitor
- inhibit