Lon-TK

Lon-TK is a glycolysis inhibitor + linker conjugate of LTB (HY-169434). LTB is an intelligent responsive prodrug that connects Lonidamine (Lon) (HY-B0486) and a PD-L1 inhibitor (BMS-1, HY-19991) through a thioketal linker. It significantly inhibits the glycolytic metabolism of tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK shows potential for application in photodynamic-enhanced immunotherapy research.

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  • 화학식: C24H28Cl2N2O3S2
  • 분자량:527.53
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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