MAX8 acetate
Based on 1 Customer Validation
MAX8 is a peptide made up of 20 residues that can fold and self-assemble under the influence of DMEM, forming a mechanically rigid hydrogel, this allows cells to be evenly immersed in the gel when the gelation is triggered in the presence of cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C106H196N28O23.xC2H4O2
- 분자량:2230.86 (free base)
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보관:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
제품 설명
Chemical Information
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Appearance Solid
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분자량 2230.86 (free base)
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화학식 C106H196N28O23.xC2H4O2
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Sequence
Val-Lys-Val-Lys-Val-Lys-Val-Lys-Val-{d-Pro}-Pro-Thr-Lys-Val-Glu-Val-Lys-Val-Lys-Val-NH2
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Sequence Shortening
VKVKVKVKV-{d-Pro}-PTKVEVKVKV-NH2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
용액&용해도
In Vitro:
H2O : 2.5 mg/mL (Need ultrasonic)
순도&문서
References
[1]. Haines-Butterick L, et al. Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells. Proceedings of the National Academy of Sciences of the United States of America. 2007 May 08;104(19):7791-6. [Content Brief]
[2]. Lindsey S, et al. Beta Hairpin Peptide Hydrogels as an Injectable Solid Vehicle for Neurotrophic Growth Factor Delivery. Biomacromolecules. 2015 Sep 14;16(9):2672-83. [Content Brief]
[3]. Hule RA, et al. Correlations between structure, material properties and bioproperties in self-assembled beta-hairpin peptide hydrogels. Faraday discussions. 2008;139:251-64; discussion 309-25, 419-20. [Content Brief]
[4]. Branco MC, et al. Fast dynamics of semiflexible chain networks of self-assembled peptides. Biomacromolecules. 2009 Jun 08;10(6):1374-80. [Content Brief]
[5]. Leonard SR, et al. Solid-state NMR evidence for β-hairpin structure within MAX8 designer peptide nanofibers. Biophysical journal. 2013 Jul 02;105(1):222-30. [Content Brief]
[6]. Sun JE, et al. Sustained release of active chemotherapeutics from injectable-solid β-hairpin peptide hydrogel. Biomaterials science. 2016 May 26;4(5):839-48. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)