MeThPmR
MeThPmR, a ribonucleoside derivative, is a potent and selective human nucleoside transporter 1 (hCNT1) inhibitor (Ki/sub> = 0.16-0.69 μM). MeThPmR exhibit weak inhibitory activity on hCNT2 (IC50 = 360 μM) and hCNT3 (Ki = 4.7 μM). MeThPmR can protect cells from the toxicity of nucleoside drugs. MeThPmR can be used for the research of cancer.
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- CAS No.: 1262032-38-1
- 화학식: C12H14N2O5S
- 분자량:298.31
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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hCNT1 0.16-0.69 μM (Ki) |
hCNT3 4.7 μM (Ki) |
hCNT2 360 μM (IC50) |
Chemical Information
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CAS No. 1262032-38-1
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분자량 298.31
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화학식 C12H14N2O5S
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SMILES
O=C1N([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C=C(C=C(C)S3)C3=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MeThPmR Related Classifications
HY-177746 Related Classifications
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